Virtual Laboratory

vLab is a package for biopharmaceutical manufacturing simulation in Python. It utilizes the diffeqpy, a python wrapper of DifferentialEquations.jl and scipy built-in ode solver for its core routines to give high performance solving of large stiff differential equations, currently including:

• N-linked Gycosylation Simulation in Perfusion Bioreactor
• Raman Spectrometry and Raman Data Analytics
• Plantwise Simulation (Cell Culture and Chromatography)

The end goal of this project is to build a modularized platform, composed of an interactive interface and a digital twin based “vLab”. The digital twin is designed to simulate end-to-end bioprocess by using state-of-the-art mechanistic models for prediction, control and risk management.