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Hybrid Model
A Modular Mechanistic In Silico Model for In Vitro Transcription Process Yield and Product Quality Prediction
In vitro transcription (IVT) plays a critical role in the manufacture of mRNA vaccines and therapeutics. Optimizing mRNA yield and …
Keqi Wang
,
Keilung Choy
,
Eli Reiser
,
Jinxiang Pei
,
Hua Zheng
,
Aparajita Dasgupta
,
Fuqiang Cheng
,
Guogang Dong
,
Bhanu Chandra Mulukutla
,
Joshua Mannheimer
,
Carolyn Huang
,
Hooman Farsani
,
Wei Xie
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DOI
Dynamic Bayesian Network Based Hybrid Process Model
This is a tutorial about a series of advanced hybrid process models for people with some background in mathematical and statistical modeling and interested in the process modeling.
Hua Zheng
May 5, 2022
15 min read
Tutorial
,
Process Modeling
,
Dynamic Bayesian Network
,
Hybrid Model
,
Inference
Opportunities of Hybrid Model-based Reinforcement Learning for Cell Therapy Manufacturing Process Development and Control
Hua Zheng
,
Wei Xie
,
Keqi Wang
,
Zheng Li
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